APC - Gene browser

APC

APC regulator of WNT signaling pathway

HCNC Approved Symbol: APC (HGNC:583)
Genomic Coordinates: 5:112,707,498 - 112,846,239 (5q22.2)
Synonyms: DP2, DP3, DP2.5, PPP1R46
Disease Associations: This gene is associated with the following 9 diseases in OMIM.

16Patients

In total, 16 patients were diagnosed with a variant in the APC gene.

(Top 5 only, Patient count*)
*% of total patients presenting each phenotype is shown in parentheses.

016
Patient count

Colon cancer: 4 (25.0%)
Patient Count: 4 (25.0%)
% of total patients presenting each phenotype is shown in parentheses.
4 (25.0%)
Colorectal polyposis: 3 (18.8%)
Patient Count: 3 (18.8%)
% of total patients presenting each phenotype is shown in parentheses.
3 (18.8%)
Microphthalmia: 2 (12.5%)
Patient Count: 2 (12.5%)
% of total patients presenting each phenotype is shown in parentheses.
2 (12.5%)
Adenomatous colonic polyposis: 1 (6.3%)
Patient Count: 1 (6.3%)
% of total patients presenting each phenotype is shown in parentheses.
1 (6.3%)
Hereditary nonpolyposis colorectal carcinoma: 1 (6.3%)
Patient Count: 1 (6.3%)
% of total patients presenting each phenotype is shown in parentheses.
1 (6.3%)