PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

HCNC Approved Symbol

PIK3CA (HGNC:8975)

Genomic Coordinates

3:179,148,126 - 179,240,093 (3q26.32)

Synonyms

PI3K

Disease Associations

This gene is associated with the following 15 diseases in OMIM.

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Disease NameOMIM IDInheritance

Breast cancer, somatic

114480-

Cerebral cavernous malformations 4, somatic

619538-

CLAPO syndrome, somatic

613089-

CLOVE syndrome, somatic

612918-

Colorectal cancer, somatic

114500-

Cowden syndrome 5

615108-

Gastric cancer, somatic

613659-

Hemifacial myohyperplasia, somatic

606773-

Hepatocellular carcinoma, somatic

114550-

Keratosis, seborrheic, somatic

182000-

Macrodactyly, somatic

155500-

Megalencephaly-capillary malformation-polymicrogyria syndrome, somatic

602501-

Nevus, epidermal, somatic

162900-

Nonsmall cell lung cancer, somatic

211980-

Ovarian cancer, somatic

167000-