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NRAS

NRAS proto-oncogene, GTPase

HCNC Approved Symbol
NRAS (HGNC:7989)
Genomic Coordinates
1:114,704,469 - 114,716,771 (1p13.2)
Synonyms
N-ras
Disease Associations
This gene is associated with the following 8 diseases in OMIM.
View More Disease Info
Disease NameOMIM IDInheritance
?RAS-associated autoimmune lymphoproliferative syndrome type IV, somatic
614470-
Colorectal cancer, somatic
114500-
Epidermal nevus, somatic
162900-
Melanocytic nevus syndrome, congenital, somatic
137550-
Neurocutaneous melanosis, somatic
249400-
Noonan syndrome 6
613224AD
Schimmelpenning-Feuerstein-Mims syndrome, somatic mosaic
163200-
Thyroid carcinoma, follicular, somatic
188470-

Diagnosed Cases

11Patients

In total, 11 patients were diagnosed with a variant in the NRAS gene.

Frequently observed phenotypes

(Top 5 only, Patient count*)
*% of total patients presenting each phenotype is shown in parentheses.

Thrombocytopenia
 4 (36.4%)
Ptosis
 2 (18.2%)
Fever
 2 (18.2%)
Hemolytic anemia
 2 (18.2%)
Neutropenia
 2 (18.2%)