Home > Gene Browser > ZNF106

ZNF106

Synonyms
SH3BP3, ZFP106, ZNF474
External resources

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
7
Likely pathogenic
8
VUS
6,322
Likely benign
445
Benign
0

Patient phenotypes

Proportions of phenotypes among 15 patients carring pathogenic or likely pathogenic variants on ZNF106 gene are displayed below.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
73.3%
Abnormality of the musculoskeletal system
66.7%
Abnormality of the eye
46.7%
Abnormality of head or neck
40%
Abnormality of limbs
26.7%
Abnormality of the integument
26.7%
Abnormality of the ear
20%
Growth abnormality
20%
Abnormality of the cardiovascular system
13.3%
Abnormality of blood and blood-forming tissues
6.7%
Abnormal cellular phenotype
0%
Abnormality of metabolism homeostasis
0%
Abnormality of prenatal development or birth
0%
Abnormality of the breast
0%
Abnormality of the digestive system
0%
Abnormality of the endocrine system
0%
Abnormality of the genitourinary system
0%
Abnormality of the immune system
0%
Abnormality of the respiratory system
0%
Abnormality of the thoracic cavity
0%
Abnormality of the voice
0%
Constitutional symptom
0%
Neoplasm
0%

Have a question or need assistance? Ask here.

Send us your questions or comments related to the variant counts and/or patient phenotypes