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WFDC9

Synonyms
WAP9, dJ688G8.2
External resources
Summary
The WAP-type four-disulfide core (WFDC) domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many members of the WFDC domain family. This gene encodes a protein which contains a WFDC domain, and is thus a member of the WFDC domain family. This gene and several other gene family members are clustered at 20q13.12.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
397
Likely benign
441
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on WFDC9 gene.

Phenotype class
Patients in 3billion (%)

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