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TRHDE

Synonyms
PAP-II, PGPEP2, TRH-DE
External resources
Summary
This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,160
Likely benign
1,479
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TRHDE gene.

Phenotype class
Patients in 3billion (%)

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