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TNP1

Synonyms
TP1
External resources
Summary
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
120
Likely benign
42
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TNP1 gene.

Phenotype class
Patients in 3billion (%)

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