Home > Gene Browser > TGM7

TGM7

Synonyms
TGMZ
External resources
Summary
Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,667
Likely benign
1,265
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TGM7 gene.

Phenotype class
Patients in 3billion (%)

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