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ST6GAL2

Synonyms
SIAT2, ST6GalII
External resources
Summary
This locus encodes a sialyltransferase. The encoded type II transmembrane protein catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. Polymorphisms at this locus may be associated with variations in risperidone response in schizophrenic patients. Alternatively spliced transcript variants have been described.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,803
Likely benign
368
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ST6GAL2 gene.

Phenotype class
Patients in 3billion (%)

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