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SLC22A11

Synonyms
OAT4, hOAT4
External resources
Summary
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,984
Likely benign
965
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on SLC22A11 gene.

Phenotype class
Patients in 3billion (%)

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