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SIGLEC6

Synonyms
CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1
External resources
Summary
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,050
Likely benign
3,009
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on SIGLEC6 gene.

Phenotype class
Patients in 3billion (%)

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