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S1PR4

Synonyms
EDG6, LPC1, S1P4, SLP4
External resources
Summary
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
617
Likely benign
2,288
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on S1PR4 gene.

Phenotype class
Patients in 3billion (%)

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