Home > Gene Browser > S1PR3

S1PR3

Synonyms
C9orf108, C9orf47, EDG-3, EDG3, LPB3, S1P3, bA791O21.3
External resources
Summary
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,107
Likely benign
1,576
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on S1PR3 gene.

Phenotype class
Patients in 3billion (%)

Have a question or need assistance? Ask here.

Send us your questions or comments related to the variant counts and/or patient phenotypes