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RGS19

Synonyms
GAIP, RGSGAIP
External resources
Summary
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,055
Likely benign
274
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on RGS19 gene.

Phenotype class
Patients in 3billion (%)

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