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POLR2G

Synonyms
RPB19, RPB7, hRPB19, hsRPB7
External resources
Summary
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,330
Likely benign
2,363
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on POLR2G gene.

Phenotype class
Patients in 3billion (%)

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