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NOL7

Synonyms
C6orf90, PQBP3, RARG-1, dJ223E5.2
External resources
Summary
The protein encoded by this gene localizes to the nucleolus, where it maintains nucleolar structure and cell growth rates. The encoded protein also functions as a tumor suppressor and regulator of angiogenesis. The RB tumor suppressor gene recruits transcription factors to this gene and positively regulates its expression. Two transcript variants encoding the same protein have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,754
Likely benign
1,721
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NOL7 gene.

Phenotype class
Patients in 3billion (%)

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