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NFAM1

Synonyms
CNAIP
External resources
Summary
The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
850
Likely benign
428
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NFAM1 gene.

Phenotype class
Patients in 3billion (%)

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