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MSN

Synonyms
HEL70, IMD50
External resources
Summary
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
646
Likely benign
1,235
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MSN gene.

Phenotype class
Patients in 3billion (%)

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