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MFN1

Synonyms
hfzo1, hfzo2
External resources
Summary
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,883
Likely benign
3,371
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MFN1 gene.

Phenotype class
Patients in 3billion (%)

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