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MEX3B

Synonyms
MEX-3B, RKHD3, RNF195
External resources
Summary
This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
13,829
Likely benign
1,309
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MEX3B gene.

Phenotype class
Patients in 3billion (%)

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