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MAVS

Synonyms
CARDIF, IPS-1, IPS1, VISA
External resources
Summary
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,391
Likely benign
334
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MAVS gene.

Phenotype class
Patients in 3billion (%)

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