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LYVE1

Synonyms
CRSBP-1, HAR, LYVE-1, XLKD1
External resources
Summary
This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
980
Likely benign
649
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on LYVE1 gene.

Phenotype class
Patients in 3billion (%)

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