Home > Gene Browser > LEO1

LEO1

Synonyms
RDL
External resources
Summary
LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
4,831
Likely benign
2,075
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on LEO1 gene.

Phenotype class
Patients in 3billion (%)

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