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IL20RA

Synonyms
CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA
External resources
Summary
This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
8,017
Likely benign
280
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on IL20RA gene.

Phenotype class
Patients in 3billion (%)

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