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HSPA4L

Synonyms
APG-1, APG1, HSPH3, Osp94
External resources
Summary
The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
17,584
Likely benign
802
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on HSPA4L gene.

Phenotype class
Patients in 3billion (%)

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