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HSP90AB1

Synonyms
D6S182, HSP84, HSP90B, HSPC2, HSPCB
External resources
Summary
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,845
Likely benign
735
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on HSP90AB1 gene.

Phenotype class
Patients in 3billion (%)

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