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GRWD1

Synonyms
CDW4, GRWD, RRB1, WDR28
External resources
Summary
This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,663
Likely benign
5,812
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on GRWD1 gene.

Phenotype class
Patients in 3billion (%)

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