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FDCSP

Synonyms
C4orf7, FDC-SP
External resources
Summary
This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
604
Likely benign
279
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FDCSP gene.

Phenotype class
Patients in 3billion (%)

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