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DRAM1

Synonyms
DRAM
External resources
Summary
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,667
Likely benign
93
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on DRAM1 gene.

Phenotype class
Patients in 3billion (%)

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