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CTF1

Synonyms
CT-1, CT1
External resources
Summary
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,914
Likely benign
2,392
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CTF1 gene.

Phenotype class
Patients in 3billion (%)

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