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CDH22

Synonyms
C20orf25, dJ998H6.1
External resources
Summary
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
23,044
Likely benign
1,194
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CDH22 gene.

Phenotype class
Patients in 3billion (%)

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