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CDCA8

Synonyms
BOR, BOREALIN, DasraB, MESRGP
External resources
Summary
This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,775
Likely benign
1,698
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CDCA8 gene.

Phenotype class
Patients in 3billion (%)

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