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CDC25C

Synonyms
CDC25, PPP1R60
External resources
Summary
This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
4,524
Likely benign
2,038
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CDC25C gene.

Phenotype class
Patients in 3billion (%)

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