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CD28

Synonyms
Tp44
External resources
Summary
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,088
Likely benign
387
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CD28 gene.

Phenotype class
Patients in 3billion (%)

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