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BTF3

Synonyms
BETA-NAC, BTF3a, BTF3b, NACB
External resources
Summary
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
17,482
Likely benign
1,686
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on BTF3 gene.

Phenotype class
Patients in 3billion (%)

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