Home > Gene Browser > ARHGAP25

ARHGAP25

Synonyms
HEL-S-308, KAIA0053
External resources
Summary
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
4,393
Likely benign
1,731
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ARHGAP25 gene.

Phenotype class
Patients in 3billion (%)

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