Home > Gene Browser > ANGPT4

ANGPT4

Synonyms
ANG3, ANG4
External resources
Summary
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,461
Likely benign
2,272
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ANGPT4 gene.

Phenotype class
Patients in 3billion (%)

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