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ACP6

Synonyms
ACPL1, LPAP, PACPL1
External resources
Summary
This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,825
Likely benign
607
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ACP6 gene.

Phenotype class
Patients in 3billion (%)

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