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ZRSR2

Synonyms
U2AF1-RS2, U2AF1L2, U2AF1RS2, URP, ZC3H22
External resources
Summary
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,107
Likely benign
1,853
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ZRSR2 gene.

Phenotype class
Patients in 3billion (%)

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