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ZNF77

Synonyms
pT1
External resources

Variant Counts

Variant classification counts, according to ACMG guideline on all identified variants among our tested samples, are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc.) are excluded.

Pathogenic
205
Likely pathogenic
10
VUS
1,466
Likely benign
1,058
Benign
0

Patient Phenotypes

Proportions of phenotypes among 212 patients carrying pathogenic or likely pathogenic variants on ZNF77 gene are displayed below. The following symptoms were found in patients with a variant in ZNF77. However, patients may have been diagnosed with a different variant.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
41%
Abnormality of the musculoskeletal system
23.6%
Abnormality of head or neck
19.3%
Abnormality of the cardiovascular system
18.9%
Abnormality of the eye
14.2%
Abnormality of the ear
11.8%
Growth abnormality
11.8%
Abnormality of blood and blood forming tissues
11.3%
Abnormality of the integument
9.4%
Abnormality of the genitourinary system
7.5%
Abnormality of metabolism homeostasis
6.6%
Abnormality of the digestive system
6.6%
Abnormality of limbs
6.1%
Abnormality of the immune system
5.2%
Abnormality of the respiratory system
2.8%
Abnormality of the endocrine system
2.4%
Neoplasm
1.9%
Abnormal cellular phenotype
1.4%
Abnormality of the breast
1.4%
Abnormality of prenatal development or birth
0.9%
Constitutional symptom
0.5%
Abnormality of the thoracic cavity
0%
Abnormality of the voice
0%

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