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ZNF727

Synonyms
ZNF727P
External resources

Variant Counts

Variant classification counts, according to ACMG guideline on all identified variants among our tested samples, are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc.) are excluded.

Pathogenic
18
Likely pathogenic
274
VUS
6,833
Likely benign
994
Benign
0

Patient Phenotypes

Proportions of phenotypes among 291 patients carrying pathogenic or likely pathogenic variants on ZNF727 gene are displayed below. The following symptoms were found in patients with a variant in ZNF727. However, patients may have been diagnosed with a different variant.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
32.6%
Abnormality of the eye
22.7%
Abnormality of the musculoskeletal system
22.7%
Abnormality of the cardiovascular system
17.5%
Abnormality of head or neck
15.1%
Abnormality of the ear
13.4%
Growth abnormality
10.3%
Abnormality of the digestive system
8.6%
Abnormality of the genitourinary system
8.6%
Abnormality of metabolism homeostasis
7.2%
Abnormality of blood and blood forming tissues
6.9%
Abnormality of the immune system
6.2%
Abnormality of limbs
5.8%
Abnormality of the integument
3.8%
Neoplasm
3.8%
Abnormality of prenatal development or birth
3.1%
Abnormality of the endocrine system
3.1%
Abnormality of the respiratory system
2.1%
Constitutional symptom
0.7%
Abnormal cellular phenotype
0.3%
Abnormality of the breast
0.3%
Abnormality of the thoracic cavity
0%
Abnormality of the voice
0%

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