Home > Gene Browser > ZNF559-ZNF177

ZNF559-ZNF177

Synonyms
-
External resources

Variant Counts

Variant classification counts, according to ACMG guideline on all identified variants among our tested samples, are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc.) are excluded.

Pathogenic
69
Likely pathogenic
0
VUS
5,773
Likely benign
1,093
Benign
0

Patient Phenotypes

Proportions of phenotypes among 69 patients carrying pathogenic or likely pathogenic variants on ZNF559-ZNF177 gene are displayed below. The following symptoms were found in patients with a variant in ZNF559-ZNF177. However, patients may have been diagnosed with a different variant.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
43.5%
Abnormality of the musculoskeletal system
31.9%
Abnormality of the cardiovascular system
23.2%
Abnormality of the eye
21.7%
Abnormality of the ear
17.4%
Abnormality of head or neck
15.9%
Abnormality of metabolism homeostasis
13%
Abnormality of the immune system
13%
Abnormality of the digestive system
11.6%
Growth abnormality
11.6%
Abnormality of the integument
8.7%
Abnormality of limbs
7.2%
Abnormality of the endocrine system
7.2%
Abnormality of blood and blood forming tissues
5.8%
Abnormality of the genitourinary system
5.8%
Neoplasm
4.3%
Abnormality of the respiratory system
2.9%
Constitutional symptom
2.9%
Abnormal cellular phenotype
1.4%
Abnormality of the breast
1.4%
Abnormality of prenatal development or birth
0%
Abnormality of the thoracic cavity
0%
Abnormality of the voice
0%

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