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ZNF473

Synonyms
ZFP100, ZN473
External resources
Summary
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,383
Likely benign
1,316
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ZNF473 gene.

Phenotype class
Patients in 3billion (%)

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