Home > Gene Browser > ZHX2

ZHX2

Synonyms
AFR1, RAF
External resources
Summary
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,082
Likely benign
897
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ZHX2 gene.

Phenotype class
Patients in 3billion (%)

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