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ZDHHC8

Synonyms
DHHC8, ZDHHCL1, ZNF378
External resources
Summary
This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
6,144
Likely benign
1,317
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ZDHHC8 gene.

Phenotype class
Patients in 3billion (%)

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