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TUBE1

Synonyms
TUBE, dJ142L7.2
External resources
Summary
This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,158
Likely benign
1,846
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TUBE1 gene.

Phenotype class
Patients in 3billion (%)

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