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TRMT2A

Synonyms
HTF9C
External resources
Summary
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,131
Likely benign
3,167
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TRMT2A gene.

Phenotype class
Patients in 3billion (%)

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