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TMEM150C

Synonyms
TTN3
External resources
Summary
This gene encodes a transmembrane protein component of a mechanosensitve ion channel that is activated by mechanical stimuli in various cell types and confers slowly adapting, mechanically activated currents in dorsal root ganglion neurons. Mechanically activated ion channels are sensors that are critical for hearing, touch, pain, and blood pressure regulation.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,167
Likely benign
3,938
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TMEM150C gene.

Phenotype class
Patients in 3billion (%)

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