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RNF141

Synonyms
RFP141, ZFP26, ZNF230
External resources
Summary
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,229
Likely benign
556
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on RNF141 gene.

Phenotype class
Patients in 3billion (%)

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