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RASEF

Synonyms
RAB45, TSG
External resources
Summary
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
13,946
Likely benign
2,537
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on RASEF gene.

Phenotype class
Patients in 3billion (%)

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